BACKGROUND: Yacon is a root crop which contains high amounts of The aim of this study was to investigate the effects of yacon syrup on. Yacon roots (Smallanthus sonchifolius) improve oxidative stress in diabetic rats. Instituto Superior de Investigaciones Biológicas (INSIBIO). Carolina Serra-. Instituto Superior de Investigaciones Biológicas (INSIBIO), Another important Andean crop is yacon (Smallanthus sonchifolius) which is a.

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In this sense, natural products provide a rich source for safe and effective therapeutic compounds with multiple mechanisms of action [ 1213 ].

Effects of yacon flour on inflammatory markers in HFD-fed rats. After clotting, samples were centrifuged and serum was used for biochemical determinations.

Publishing contents in this journal does not generate royalties for contributors. Colorimetric method for determinations of sugars and related substances. It is well established that high-fat diet impairs gastrointestinal peptides secretion, implicated in appetite control and insulin release [ 31 ]. Gcg a and infestigaciones YY: Rats were kept in a breeding room with controlled environment temperature: Previous Article Next Article.

Effect of yacon (Smallanthus sonchifolius) on colonic transit time in healthy volunteers.

HFD Y original magnification X. Robinson belongs to a member of Asteraceae family, which ranges through the Andean region in South America [ 1415 ]. Investigqciones data indicate that yacon attenuates diet-induced obesity in rats by decreasing fat absorption.

Published Dec 14, Yacon Improves the Effects of the Reversion to Standard Diet To identify whether the yacon supplementation potentiate the effects of the HFD reversion to a standard diet, we performed a second experimental design.

Pharm Biol Aug 8;53 8: Andean roots and tubers are underexploited crops; many contain compounds beneficial to health, so a greater knowledge of their properties is important for encouraging their consumption. You do not ingestigaciones JavaScript enabled.


Yacon roots (Smallanthus sonchifolius) improve oxidative stress in diabetic rats. | PubFacts

Interestingly, differences in fat deposition in terms of epididymal, perirenal, and mesenteric pads, were observed after yacon supplementation. Biochemical and Biophysical Research Communications. The expansion of adipose tissue begins when differentiated adipocytes rapidly respond to nutrient excess acting as lipid-synthesizing and lipid storing cells [ 5 ].

The extra energy is stored as triglyceride in adipose tissue through an adipogenic process and accumulated in ectopic sites like muscle and liver, leading to a metabolic dysfunction [ 23 ]. Recently, long-term consumption of yacon syrup has been shown to improve insulin resistance and reduce body weight in premenopausal women [ 30 ].

Yacon markedly accelerates colonic transit in yafon individuals. The treatment of diabetic rats produced an increase of glutathione peroxidase and glutathione levels in liver In accordance with this finding, fasting glucose, glucose tolerance, and insulin resistance were also improved being the blood glucose concentrations similar to those of the SD rats during the glucose challenges Figures 7 f and 7 g. Others are allowed to quote, adapt, transform, auto-archive, republish, and create based on this material, for any purpose even commercial onesprovided the authorship is duly acknowledged, a link to the original work is provided, and it is specified if changes have been made.

At this time, animals fed HFD reached obesity status Figure 1. Still can’t find the full text of the article? Back to tab navigation Download options Please wait Dek intestinal uptake is a crucial step for obesity progression and hyperlipidemia. In order to assess whether the yacon invesgigaciones lipid ijvestigaciones at the intestinal level, we perform an oral triglyceride loading test. Andean yacon root Smallanthus sonchifolius Poepp.

Fat pad weights are expressed as the sum of visceral, retroperitoneal, and epididymal weights. Experimental studies have demonstrated that the addition of oligofructose to the diet improves the growth of Bifidus and Lactobacillus in the colon enhancing mineral absorption and gastrointestinal metabolism in both humans and animals [ 1619 ].


Epub Apr 8. The article was received on 20 Feb investitaciones, accepted on 18 Jul and first published on 20 Jul In a second design, after 12 weeks rats which fed standard diet hacon with the same chow, while animals under HFD were changed to a standard diet with or without yacon, according to the following scheme Figure 1.

Effect of yacon (Smallanthus sonchifolius) on colonic transit time in healthy volunteers.

These findings raise the interesting possibility that adipose tissue could be a target organ of the yacon roots in the management of obesity. The aim of this research was to optimize the parameters for the vacuum impregnation of aloe vera into dried yacon Smallanthus sonchifolius Poepp.

The high-density lipoprotein cholesterol HDLc was determined after precipitation of very low-density lipoprotein VLDL and low-density lipoprotein LDLc with polyanions dextran sulphate and magnesium chloride. Food Chem Toxicol January – June Bioengineering and chemical engineering plugins. As previously reported by us, yacon roots exhibit a lipid lowering effect, mainly reducing serum triglycerides and VLDLc levels, in normal and diabetic rats [ 1725 ].

Moreover, in human studies, we demonstrate that yacon syrup lowers plasma lipid concentrations and decreases glycemia in patients with insulin resistance [ 30 ].

Increasing evidence indicates that the excessive fat depots, particularly visceral adiposity, are linked to a chronic low-grade inflammatory state [ 145 ]. Yacon supplementation reduced the expression of the mentioned markers in HFD-fed animals Figures 4 a — 4 c. It is well recognized that FOS could also be a fermentable substrate for the colon microbiota, being low polymerization FOS DP the most used by Bifidobacterium spp.